I would like to thank the members of the Botstein lab for valuable discussions and feedback, in particular Michael Shapira, John Murray, Maitreya Dunham, Barbera Dunn, Matt Brauer, Michal Ronen and my advisor David Botstein.

I would also like to thank the many other people both inside and outside of Stanford who have given me feedback, including Jason Lieb, Christian Rees, John Matese, Gavin Sherlock, Michiel Jan Laurens de Hoon and Stéphane Graziani.